NEK3 antibody (AA 331-361)

Catalog No. ABIN652427

Product Details anti-NEK3 Antibody

Target: NEK3 (NIMA related kinase 3 (NEK3))

Binding Specificity: AA 331-361

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NEK3 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This NEK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 331-361 amino acids from the Central region of human NEK3.

Clone: RB2961

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:2000. WB: 1:2000. WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-NEK3 antibody (ABIN652427)

McHale, Tomaszewski, Puthiyaveettil, Livolsi, Clevenger: "Altered expression of prolactin receptor-associated signaling proteins in human breast carcinoma." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 21, Issue 5, pp. 565-71, (2008) (PubMed).

Target Details for NEK3

Target: NEK3 (NIMA related kinase 3 (NEK3))

Alternative Name: NEK3 (NEK3 Products)

Synonyms: HSPK36 antibody, ATNEK3 antibody, NIMA-RELATED KINASE3 antibody, NIMA-related kinase 3 antibody, T8M17.60 antibody, T8M17_60 antibody, NIMA related kinase 3 antibody, NIMA (never in mitosis gene a)-related expressed kinase 3 antibody, NIMA-related kinase 3 S homeolog antibody, NIMA-related kinase 3 antibody, NEK3 antibody, Nek3 antibody, nek3.S antibody

Background: In Aspergillus nidulans, lack of the serine/threonine kinase NimA (never in mitosis A) results in cell cycle arrest in G2, while overexpression causes the premature onset of mitotic events. NEK3 is similar in sequence to the Aspergillus nidulans protein and may therefore play a role in mitotic regulation. However, the encoded protein differs from other NimA family members in that it is not cell cycle regulated and is found primarily in the cytoplasm.

Molecular Weight: 57705

NCBI Accession: NP_001139571, NP_002489, NP_689933

UniProt: P51956