MUC20 antibody (C-Term)

Catalog No. ABIN652400

Product Details anti-MUC20 Antibody

Target: MUC20 (Mucin 20, Cell Surface Associated (MUC20))

Binding Specificity: AA 654-684, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MUC20 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MUC20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 654-684 amino acids from the C-terminal region of human MUC20.

Clone: RB13033

Isotype: Ig Fraction

Application Details

Application Notes: IF: 1:10~50. WB: 1:1000. IHC-P-Leica: 1:500. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-MUC20 antibody (ABIN652400)

Uchino, Woodward, Argüeso: "Differential effect of rebamipide on transmembrane mucin biosynthesis in stratified ocular surface epithelial cells." in: Experimental eye research, Vol. 153, pp. 1-7, (2017) (PubMed).

Ohmori, Fujii, Kadochi, Mori, Nishiguchi, Fujiwara, Kishi, Sasaki, Kuniyasu: "Elaidic Acid, a Trans-Fatty Acid, Enhances the Metastasis of Colorectal Cancer Cells." in: Pathobiology : journal of immunopathology, molecular and cellular biology, Vol. 84, Issue 3, pp. 144-151, (2017) (PubMed).

Woodward, Argüeso: "Expression analysis of the transmembrane mucin MUC20 in human corneal and conjunctival epithelia." in: Investigative ophthalmology & visual science, Vol. 55, Issue 10, pp. 6132-8, (2014) (PubMed).

Target Details for MUC20

Target: MUC20 (Mucin 20, Cell Surface Associated (MUC20))

Alternative Name: MUC20 (MUC20 Products)

Synonyms: BC026367 antibody, MUC-20 antibody, mucin-20 antibody, mucin 20 antibody, mucin 20, cell surface associated antibody, LOC750119 antibody, Muc20 antibody, MUC20 antibody

Background: This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins secreted by many epithelial tissues to form an insoluble mucous barrier. The shorter isoform expressed by this gene is localized to the plasma membrane, whereas the longer isoform might be secreted. The C terminus of this protein associates with the multifunctional docking site of the met proto-oncogene and suppresses activation of some downstream met signaling cascades. The protein features a tandem repeat domain that varies between 2 and 6 copies in different individuals. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 71982

Gene ID: 200958

UniProt: Q8N307