Vitronectin antibody (N-Term)

Catalog No. ABIN652347

Product Details anti-Vitronectin Antibody

Target: Vitronectin (VTN)

Binding Specificity: AA 65-93, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Vitronectin antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This VTN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 65-93 amino acids from the N-terminal region of human VTN.

Clone: RB17843

Isotype: IgG

Application Details

Application Notes: WB: 1:32000. WB: 1:2000. IHC-P: 1:10~50. FC: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-Vitronectin antibody (ABIN652347)

Lamar, Stern, Liu, Schindler, Jiang, Hynes: "The Hippo pathway target, YAP, promotes metastasis through its TEAD-interaction domain." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 37, pp. E2441-50, (2012) (PubMed).

Target Details for Vitronectin

Target: Vitronectin (VTN)

Alternative Name: VTN (VTN Products)

Synonyms: VTN antibody, DKFZp470F0511 antibody, LOC100228142 antibody, vtn antibody, zgc:112277 antibody, V75 antibody, VN antibody, VNT antibody, AI256434 antibody, Vn antibody, Aa1018 antibody, vitronectin antibody, vitronectin a antibody, vitronectin b antibody, vitronectin L homeolog antibody, VTN antibody, vtn antibody, vtna antibody, vtnb antibody, CpipJ_CPIJ016691 antibody, vtn.L antibody, Vtn antibody

Background: VTN is a member of the pexin family. This protein is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. The protein is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond.

Molecular Weight: 54306

Gene ID: 7448

NCBI Accession: NP_000629

UniProt: P04004

Pathways: Autophagy, Smooth Muscle Cell Migration