SCYL1 antibody (N-Term)

Catalog No. ABIN652299

This anti-SCYL1 antibody is a Rabbit Polyclonal antibody detecting SCYL1 in WB and IHC (p). Suitable for Human.

Quick Overview for SCYL1 antibody (N-Term) (ABIN652299)

Target: SCYL1 (SCY1-Like 1 (SCYL1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCYL1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB9791

Product Details anti-SCYL1 Antibody

Binding Specificity: AA 156-185, N-Term

Predicted Reactivity: B

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SCYL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-185 amino acids from the N-terminal region of human SCYL1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for SCYL1

Target: SCYL1 (SCY1-Like 1 (SCYL1))

Alternative Name: SCYL1

Background: SCYL1 forms multimers following transfection into COS-7 cells. SCYL1 forms a 300-kD trimer using crosslinking reagents. Biochemical analysis revealed no phosphorylation or autophosphorylation activity.The 707-amino acid SCYL1 variant, variant 2, localized to centrosomes during mitosis. During interphase, fluorescence-tagged variant 2 localized in the cytoplasm as well as centrosomes. However, at the beginning of mitosis, the fluorescence appeared as a pair of bright nuclear foci that followed centrosome localization throughout mitosis, while maintaining diffuse cytoplasmic labeling. Endogenous variant 2 in HeLa cells showed a similar staining pattern. Centrosomal localization was independent of microtubules.

Molecular Weight: 89631

Gene ID: 57410

NCBI Accession: NP_001041683, NP_065731

UniProt: Q96KG9

Pathways: p53 Signaling