Synapsin III antibody (AA 363-388)

Catalog No. ABIN651941

Product Details anti-Synapsin III Antibody

Target: Synapsin III (SYN3)

Binding Specificity: AA 363-388

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Synapsin III antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SYN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 363-388 amino acids from the Central region of human SYN3.

Clone: RB21345

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for Synapsin III

Target: Synapsin III (SYN3)

Alternative Name: SYN3 (SYN3 Products)

Synonyms: SYN3 antibody, syn3-A antibody, synapsin-3 antibody, synapsin III antibody, synapsin III L homeolog antibody, LOC100146694 antibody, SYN3 antibody, syn3.L antibody, syn3 antibody, Syn3 antibody

Background: This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. The protein encoded by this gene shares the synapsin family domain model, with domains A, C, and E exhibiting the highest degree of conservation. The protein contains a unique domain J, located between domains C and E. Based on this gene's localization to 22q12.3, a possible schizophrenia susceptibility locus, and the established neurobiological roles of the synapsins, this family member may represent a candidate gene for schizophrenia. The TIMP3 gene is located within an intron of this gene and is transcribed in the opposite direction.

Molecular Weight: 63303

Gene ID: 8224

NCBI Accession: NP_003481, NP_598344

UniProt: O14994