IKZF3 antibody (AA 76-103)

Catalog No. ABIN651843

Product Details anti-IKZF3 Antibody

Target: IKZF3 (IKAROS Family Zinc Finger 3 (Aiolos) (IKZF3))

Binding Specificity: AA 76-103

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IKZF3 antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: B

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This IKZF3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 76-103 amino acids from the Central region of human IKZF3.

Clone: RB30017

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for IKZF3

Target: IKZF3 (IKAROS Family Zinc Finger 3 (Aiolos) (IKZF3))

Alternative Name: IKZF3 (IKZF3 Products)

Background: This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described.

Molecular Weight: 58023

Gene ID: 22806

NCBI Accession: NP_001244337, NP_001244338, NP_001244339, NP_001244340, NP_001244341, NP_001244342, NP_001244343, NP_036613, NP_899051, NP_899052, NP_899053, NP_899054, NP_899055

UniProt: Q9UKT9