EID2 antibody (C-Term)

Catalog No. ABIN651820

Product Details anti-EID2 Antibody

Target: EID2 (EP300 Interacting Inhibitor of Differentiation 2 (EID2))

Binding Specificity: AA 177-208, C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EID2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This EID2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 177-208 amino acids from the C-terminal region of human EID2.

Clone: RB27209

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for EID2

Target: EID2 (EP300 Interacting Inhibitor of Differentiation 2 (EID2))

Alternative Name: EID2 (EID2 Products)

Synonyms: CRI2 antibody, EID-2 antibody, Cri2 antibody, EP300 interacting inhibitor of differentiation 2 antibody, EID2 antibody, Eid2 antibody

Background: EID2 interacts with EP300 and acts as a repressor of MYOD-dependent transcription and muscle differentiation. Inhibits EP300 histone acetyltransferase activity. Acts as a repressor of TGFB/SMAD transcriptional responses. It may act as a repressor of the TGFB/SMAD3-dependent signaling by selectively blocking formation of TGFB-induced SMAD3-SMAD4 complex.

Molecular Weight: 25190

Gene ID: 163126

NCBI Accession: NP_694964

UniProt: Q8N6I1