TNIP3 antibody (N-Term)
TNIP3
Reactivity: Human
WB, IHC (p)
Host: Rabbit
Polyclonal
RB27057
unconjugated
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- Target See all TNIP3 Antibodies
- TNIP3 (TNFAIP3 Interacting Protein 3 (TNIP3))
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Binding Specificity
- AA 74-102, N-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TNIP3 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This TNIP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74-102 amino acids from the N-terminal region of human TNIP3.
- Clone
- RB27057
- Isotype
- Ig Fraction
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anti-TNFAIP3 Interacting Protein 3 (TNIP3) (C-Term) antibody
TNIP3 Reactivity: Human, Mouse WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB: 1:1000. IHC-P: 1:50~100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Expiry Date
- 6 months
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- Target
- TNIP3 (TNFAIP3 Interacting Protein 3 (TNIP3))
- Alternative Name
- TNIP3 (TNIP3 Products)
- Synonyms
- ABIN-3 antibody, LIND antibody, 9030611K07Rik antibody, TNIP3 antibody, TNFAIP3 interacting protein 3 antibody, TNIP3 antibody, Tnip3 antibody
- Background
- TNIP3 binds to zinc finger protein TNFAIP3 and inhibits NF-kappa-B activation induced by tumor necrosis factor, Toll-like receptor 4 (TLR4), interleukin-1 and 12-O-tetradecanoylphorbol-13-acetate. It Overexpression inhibits NF-kappa-B-dependent gene expression in response to lipopolysaccharide at a level downstream of TRAF6 and upstream of IKBKB. NF-kappa-B inhibition is independent of TNFAIP3 binding.
- Molecular Weight
- 38943
- Gene ID
- 79931
- NCBI Accession
- NP_001122315, NP_001231693, NP_079149
- UniProt
- Q96KP6
- Pathways
- Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin
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