Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Predicted Reactivity
B, M, Rat
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This SDHAF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 34-62 amino acids from the Central region of human SDHAF1.
The succinate dehydrogenase (SDH) complex (or complex II) of the mitochondrial respiratory chain is composed of 4 individual subunits. The protein encoded by this gene resides in the mitochondria, and is essential for SDH assembly, but does not physically associate with the complex in vivo. Mutations in this gene are associated with SDH-defective infantile leukoencephalopathy (mitochondrial complex II deficiency).