This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This HIST1H2AK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human HIST1H2AK.
H2A/d antibody, H2AFD antibody, histone cluster 1 H2A family member k antibody, histone cluster 1, H2ak antibody, HIST1H2AK antibody, Hist1h2ak antibody
Background
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family.