Adrenomedullin antibody (AA 69-96)

Catalog No. ABIN651196

Product Details anti-Adrenomedullin Antibody

Target: Adrenomedullin (ADM)

Binding Specificity: AA 69-96

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Adrenomedullin antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Predicted Reactivity: B

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ADM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 69-96 amino acids of human ADM.

Clone: RB23214

Isotype: IgG

Application Details

Application Notes: WB: 1:1000. WB: 1:1000-1:2000. WB: 1:2000. FC: 1:10~50. FC: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for Adrenomedullin

Target: Adrenomedullin (ADM)

Alternative Name: ADM (ADM Products)

Synonyms: ADM antibody, Ap antibody, H39316 antibody, RATAP antibody, AM antibody, adrenomedullin antibody, ADM antibody, adm antibody, Adm antibody

Target Type: Hormone

Background: ADM, a hypotensive peptide found in human pheochromocytoma, consists of 52 amino acids, has 1 intramolecular disulfide bond, and shows a slight homology with the calcitonin gene-related peptide. It may function as a hormone in circulation control because it is found in blood in a considerable concentration. The precursor, called preproadrenomedullin, is 185 amino acids long. By RNA-blot analysis, human adrenomedullin mRNA was found to be highly expressed in several tissues. Genomic ADM DNA consists of 4 exons and 3 introns, with the 5-prime flanking region containing TATA, CAAT, and GC boxes.

Molecular Weight: 20420

Gene ID: 133

NCBI Accession: NP_001115

UniProt: P35318

Pathways: Hormone Transport, Hormone Activity, C21-Steroid Hormone Metabolic Process, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Tube Formation