YME1L1 antibody (N-Term)

Catalog No. ABIN651076

Product Details anti-YME1L1 Antibody

Target: YME1L1 (YME1-Like 1 (YME1L1))

Binding Specificity: AA 191-219, N-Term

Reactivity: Human, Hamster

Host: Rabbit

Clonality: Polyclonal

Conjugate: This YME1L1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This YMEL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 191-219 amino acids from the N-terminal region of human YMEL1.

Clone: RB24746

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-YME1L1 antibody (ABIN651076)

Parajuli, Shrum, Tobacyk, Harb, Arthur, MacMillan-Crow: "Renal cold storage followed by transplantation impairs expression of key mitochondrial fission and fusion proteins." in: PLoS ONE, Vol. 12, Issue 10, pp. e0185542, (2017) (PubMed).

Target Details for YME1L1

Target: YME1L1 (YME1-Like 1 (YME1L1))

Alternative Name: YMEL1 (YME1L1 Products)

Synonyms: FtsH1 antibody, Ftsh antibody, FTSH antibody, MEG4 antibody, PAMP antibody, YME1L antibody, YME1-like 1 (S. cerevisiae) antibody, YME1-like 1 ATPase antibody, YME1 like 1 ATPase antibody, Yme1l1 antibody, YME1L1 antibody

Background: YMEL1 is the human ortholog of yeast mitochondrial AAA metalloprotease, Yme1p. It is localized in the mitochondria and can functionally complement a yme1 disruptant yeast strain. It is proposed that this gene plays a role in mitochondrial protein metabolism and could be involved in mitochondrial pathologies.

Molecular Weight: 86455

Gene ID: 10730

NCBI Accession: NP_001240795, NP_055078, NP_647473

UniProt: Q96TA2