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AFT1 antibody (C-Term)
AFT1
Reactivity: Human
WB, FACS
Host: Rabbit
Polyclonal
RB22228
unconjugated
Product Details anti-AFT1 Antibody
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Target
See all AFT1 Antibodies
AFT1
(Activating Transcription Factor 1 (AFT1))
Binding Specificity
All epitopes for AFT1 antibodies
AA 193-219, C-Term
Reactivity
All reactivities for AFT1 antibodies
Human
Host
All hosts for AFT1 antibodies
Rabbit
Clonality
All clonalities for AFT1 antibodies
Polyclonal
Conjugate
All conjugates for AFT1 antibodies
This AFT1 antibody is un-conjugated
Application
All applications for AFT1 antibodies
Western Blotting (WB), Flow Cytometry (FACS)
Predicted Reactivity
B
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This ATF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 193-219 amino acids from the C-terminal region of human ATF1.
Clone
RB22228
Isotype
Ig Fraction
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Alternatives
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Application Details
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Application Notes
WB: 1:1000. FC: 1:10~50
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date
6 months
Target Details for AFT1
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Target
AFT1
(Activating Transcription Factor 1 (AFT1))
Alternative Name
ATF1 (AFT1 Products )
Synonyms
ews-atf1 antibody, fus/atf-1 antibody, treb36 antibody, ATF1 antibody, EWS-ATF1 antibody, FUS/ATF-1 antibody, TREB36 antibody, Atf-1 antibody, wu:fc92c07 antibody, zgc:64099 antibody, activating transcription factor 1 antibody, activating transcription factor 1 L homeolog antibody, atf1 antibody, ATF1 antibody, MGC85066 antibody, atf1.L antibody, Atf1 antibody
Background
ATF1 binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. ATF1 binds to the Tax-responsive element (TRE) of HTLV-I. ATF1 mediates PKA-induced stimulation of CRE-reporter genes.
Molecular Weight
29233
Gene ID
466
NCBI Accession
NP_005162
UniProt
P18846
Pathways
Neurotrophin Signaling Pathway , Activation of Innate immune Response , Myometrial Relaxation and Contraction , Toll-Like Receptors Cascades
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