This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This TOX3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 214-242 amino acids from the Central region of human TOX3.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date
6 months
Han, Yue, Yang, Jian, Ma, Liu: "TOX3 protein expression is correlated with pathological characteristics in breast cancer." in: Oncology letters, Vol. 11, Issue 3, pp. 1762-1768, (2016) (PubMed).
Target
TOX3
(TOX High Mobility Group Box Family Member 3 (TOX3))
TNRC9 antibody, cagf9 antibody, tnrc9 antibody, CAGF9 antibody, 500-9 antibody, BC052044 antibody, C230068E13 antibody, Tnrc9 antibody, TOX high mobility group box family member 3 antibody, TOX3 antibody, tox3 antibody, Tox3 antibody
Background
TOX3 contains an HMG-box, indicating that it may be involved in bending and unwinding of DNA and alteration of chromatin structure. The C-terminus of the encoded protein is glutamine-rich due to CAG repeats in the coding sequence. A minor allele of this gene has been implicated in an elevated risk of breast cancer.