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HIF1A antibody (N-Term)
HIF1A
Reactivity: Human, Hamster
WB, IF, IHC (p)
Host: Rabbit
Polyclonal
RB11679
unconjugated
Product Details anti-HIF1A Antibody
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Target
See all HIF1A Antibodies
HIF1A
(Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A))
Binding Specificity
All epitopes for HIF1A antibodies
AA 1-30, N-Term
Reactivity
All reactivities for HIF1A antibodies
Human, Hamster
Host
All hosts for HIF1A antibodies
Rabbit
Clonality
All clonalities for HIF1A antibodies
Polyclonal
Conjugate
All conjugates for HIF1A antibodies
This HIF1A antibody is un-conjugated
Application
All applications for HIF1A antibodies
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Predicted Reactivity
B
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This HIF1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human HIF1A.
Clone
RB11679
Isotype
Ig Fraction
Top Product
Discover our top product HIF1A Primary Antibody
Alternatives
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anti-Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A) (AA 341-450) antibody
HIF1A
Reactivity: Human, Mouse, Rat, Rabbit
WB, ELISA, IP, FACS, IHC (p), IF (cc), IF (p), IHC (fro)
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
IF: 1:10~50. WB: 1:1000. IHC-P: 1:10~50
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date
6 months
References for anti-HIF1A antibody (ABIN650972)
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Ling, Feng, Ke, Fan, Li, Li, Dong, Wang, Xu, Li, Wang : "Metformin inhibits proliferation and enhances chemosensitivity of intrahepatic cholangiocarcinoma cell lines. " in: Oncology reports , Vol. 31 , Issue 6 , pp. 2611-8 , (2014 ) (PubMed ).
Target Details for HIF1A
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Target
HIF1A
(Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A))
Alternative Name
HIF1A (HIF1A Products )
Synonyms
hif1a antibody, AA959795 antibody, HIF1alpha antibody, MOP1 antibody, bHLHe78 antibody, HIF-1A antibody, HIF-1alpha antibody, HIF1 antibody, HIF1-ALPHA antibody, PASD8 antibody, HIF1-alpha antibody, hif-1a antibody, hypoxia inducible factor 1 alpha antibody, hypoxia inducible factor 1, alpha subunit antibody, hypoxia inducible factor 1 alpha subunit antibody, HIF (Hypoxia Inducible Factor) homologa antibody, hif-1a antibody, Hif1a antibody, HIF1A antibody, hif1a antibody, hif-1 antibody
Background
Hypoxia-inducible factor-1 (HIF1) is a transcription factor found in mammalian cells cultured under reduced oxygen tension that plays an essential role in cellular and systemic homeostatic responses to hypoxia. HIF1 is a heterodimer composed of an alpha subunit and a beta subunit. The beta subunit has been identified as the aryl hydrocarbon receptor nuclear translocator (ARNT). This protein encodes the alpha subunit of HIF-1. Overexpression of a natural antisense transcript (aHIF) of this gene has been shown to be associated with nonpapillary renal carcinomas.
Molecular Weight
92670
Gene ID
3091
NCBI Accession
NP_001230013 , NP_001521 , NP_851397
UniProt
Q16665
Pathways
Positive Regulation of Peptide Hormone Secretion , Regulation of Hormone Metabolic Process , Regulation of Hormone Biosynthetic Process , Cellular Response to Molecule of Bacterial Origin , Carbohydrate Homeostasis , Transition Metal Ion Homeostasis , Tube Formation , Regulation of Carbohydrate Metabolic Process , Signaling Events mediated by VEGFR1 and VEGFR2 , VEGFR1 Specific Signals , Warburg Effect
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