This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This PIGM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 394-423 amino acids from the C-terminal region of human PIGM.
PEANUT 1 antibody, GPI-MT-I antibody, 4933437L05Rik antibody, AI644422 antibody, AV302080 antibody, C920011G20Rik antibody, PIG-M antibody, mannosyltransferase family protein antibody, phosphatidylinositol glycan anchor biosynthesis class M antibody, phosphatidylinositol glycan anchor biosynthesis, class M antibody, PNT1 antibody, PIGM antibody, Pigm antibody
Background
PIGM encodes a transmembrane protein that is located in the endoplasmic reticulum and is involved in GPI-anchor biosynthesis. The glycosylphosphatidylinositol (GPI)-anchor is a glycolipid which contains three mannose molecules in its core backbone. The GPI-anchor is found on many blood cells and serves to anchor proteins to the cell surface. PIGM encodes a mannosyltransferase, GPI-MT-I, that transfers the first mannose to GPI on the lumenal side of the endoplasmic reticulum.