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VEGFR2/CD309 antibody (pTyr1175)
VEGFR2
Reactivity: Human
DB
Host: Rabbit
Polyclonal
RB25841
unconjugated
Product Details anti-VEGFR2/CD309 Antibody
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Target
See all VEGFR2/CD309 (VEGFR2) Antibodies
VEGFR2/CD309 (VEGFR2)
(VEGF Receptor 2 (VEGFR2))
Binding Specificity
All epitopes for VEGFR2/CD309 antibodies
pTyr1175
Reactivity
All reactivities for VEGFR2/CD309 antibodies
Human
Host
All hosts for VEGFR2/CD309 antibodies
Rabbit
Clonality
All clonalities for VEGFR2/CD309 antibodies
Polyclonal
Conjugate
All conjugates for VEGFR2/CD309 antibodies
This VEGFR2/CD309 antibody is un-conjugated
Application
All applications for VEGFR2/CD309 antibodies
Dot Blot (DB)
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This KDR Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y1175 of human KDR.
Clone
RB25841
Isotype
Ig Fraction
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Alternatives
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Application Details
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Application Notes
DB: 1:500
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date
6 months
Target Details for VEGFR2/CD309
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Target
VEGFR2/CD309 (VEGFR2)
(VEGF Receptor 2 (VEGFR2))
Alternative Name
KDR (VEGFR2 Products )
Synonyms
CD309 antibody, FLK1 antibody, VEGFR antibody, VEGFR2 antibody, 6130401C07 antibody, Flk-1 antibody, Flk1 antibody, Krd-1 antibody, Ly73 antibody, VEGFR-2 antibody, sVEGFR-2 antibody, Vegfr-2 antibody, FLK-1 antibody, flk-1 antibody, vegfr-2 antibody, KDR antibody, FLK/KDR antibody, flk1 antibody, flk1b antibody, kdrb antibody, si:busm1-205d10.1 antibody, si:ch211-254j6.1 antibody, si:ch211-278f21.4 antibody, wu:fc31a09 antibody, fk52c05 antibody, flk antibody, kdr antibody, kdra antibody, vegfr2 antibody, vegfr4 antibody, vegr2 antibody, wu:fk52c05 antibody, kinase insert domain receptor antibody, kinase insert domain protein receptor antibody, vascular endothelial growth factor receptor kdr-like antibody, kinase insert domain receptor (a type III receptor tyrosine kinase) antibody, kinase insert domain receptor like antibody, KDR antibody, Kdr antibody, LOC100136647 antibody, kdr antibody, kdrl antibody
Background
Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc..
Molecular Weight
151527
Gene ID
3791
NCBI Accession
NP_002244
UniProt
P35968
Pathways
RTK Signaling , Glycosaminoglycan Metabolic Process , Signaling Events mediated by VEGFR1 and VEGFR2 , Growth Factor Binding , Regulation of long-term Neuronal Synaptic Plasticity , VEGF Signaling
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