HIST1H4A antibody (2meLys20)

Catalog No. ABIN650815

Product Details anti-HIST1H4A Antibody

Target: HIST1H4A (Histone Cluster 1, H4a (HIST1H4A))

Binding Specificity: 2meLys20, AA 1-30

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HIST1H4A antibody is un-conjugated

Application: Western Blotting (WB), Dot Blot (DB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This H4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from human H4.

Clone: RB17115

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50. DB: 1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for HIST1H4A

Target: HIST1H4A (Histone Cluster 1, H4a (HIST1H4A))

Alternative Name: H4 (HIST1H4A Products)

Synonyms: Hist1h4a antibody, H4FA antibody, histone cluster 1, H3f antibody, histone cluster 1 H4 family member a antibody, histone cluster 1, H4a antibody, Hist1h3f antibody, HIST1H4A antibody, Hist1h4a antibody

Background: Histone proteins H3, H4, H2A, and H2B function as building blocks to package eukaryotic DNA into repeating nucleosome units that are folded in higher order chromatin fibers. The nucleosome is composed of an octamer containing a H3/H4 tetramer and two H2A/H2B dimers, surrounded by approximately 146 base pairs of DNA. A diverse and elaborate array of post-translational modifications including acetylation, phosphorylation, methylation, ubiquitination, and ADP-ribosylation occurs on the N-terminal tail domains of histones.

Molecular Weight: 11367

Gene ID: 554313

NCBI Accession: NP_001029249, NP_003486, NP_003529, NP_003530, NP_003531, NP_003532, NP_003533, NP_003534, NP_003535, NP_003536, NP_003537, NP_003539, NP_068803, NP_778224

UniProt: P62805