USP29 antibody (AA 660-690)

Catalog No. ABIN650701

Product Details anti-USP29 Antibody

Target: USP29 (Ubiquitin Specific Peptidase 29 (USP29))

Binding Specificity: AA 660-690

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This USP29 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This USP29 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 660-690 amino acids from the Central region of human USP29.

Clone: RB4373

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for USP29

Target: USP29 (Ubiquitin Specific Peptidase 29 (USP29))

Alternative Name: USP29 (USP29 Products)

Synonyms: USP29 antibody, HOM-TES-84/86 antibody, Ocat antibody, universal stress protein antibody, ubiquitin specific peptidase 29 antibody, ubiquitin carboxyl-terminal hydrolase 29-like antibody, RR_RS07250 antibody, Usp29 antibody, USP29 antibody, LOC100341314 antibody, LOC100341826 antibody, LOC100342339 antibody, LOC100348359 antibody

Background: Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.

Molecular Weight: 104156

Gene ID: 57663

NCBI Accession: NP_065954

UniProt: Q9HBJ7