This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This GDF10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 317-344 amino acids from the Central region of human GDF10.
GDF10 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in mice suggest that the protein encoded by this gene plays a role in skeletal morphogenesis.