Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Predicted Reactivity
C, M
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This PDGFC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74-103 amino acids from the N-terminal region of human PDGFC.
Platelet-derived growth factor C (PDGFC) is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. PDGFC seems to form only homodimers, where the dimers are connected by disulfide bonds. It differs from the platelet-derived growth factor alpha (PDGFA) and beta (PDGFB) in having an unusual N-terminal domain, the CUB domain.