CRISP3 antibody

Catalog No. ABIN648781

Product Details anti-CRISP3 Antibody

Target: CRISP3 (Cysteine-Rich Secretory Protein 3 (CRISP3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CRISP3 antibody is un-conjugated

Application: Flow Cytometry (FACS), Cell-ELISA (cELISA)

Specificity: FACS,Cell-ELISA

Purification: Protein G

Immunogen: genetic immunisation with cDNA encoding human Crisp3

Clone: LV-2A2

Isotype: IgG1

Application Details

Application Notes: Flow cytometry: 1.2 µg/10^6 cells
CELISA: 1:200 - 1:400
For each application a titration should be performed to determine the optimal concentration.

Restrictions: For Research Use only

Handling

Concentration: 2 mg/mL

Buffer: PBS, pH 7.2

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C

Storage Comment: short term: 2 °C - 8 °C, long term: -20 °C

Target Details for CRISP3

Target: CRISP3 (Cysteine-Rich Secretory Protein 3 (CRISP3))

Alternative Name: Crisp3 (CRISP3 Products)

Synonyms: aln-a antibody, crisp3 antibody, MGC76177 antibody, CRISP3 antibody, Aeg2 antibody, CRISP-3 antibody, CRS3 antibody, SGP28 antibody, dJ442L6.3 antibody, AEG2 antibody, HSP-3 antibody, cysteine-rich secretory protein 3 antibody, cysteine-rich secretory protein 3 S homeolog antibody, cysteine rich secretory protein 3 antibody, cysteine-rich secretory protein 2 antibody, CRISP3 antibody, crisp3.S antibody, crisp3 antibody, CpipJ_CPIJ001507 antibody, Crisp3 antibody, LOC481834 antibody

Background: Cysteine-rich secretory protein 3 (CRISP3) belongs to the cysteine-rich secretory protein family. CRISPs are characterized by a cysteine-rich domain at the COOH terminal that form 8 intramolecular disulfide bonds. Mammalian members of the CRISP family are expressed predominantly in the male reproductive tract and are implicated in the process of reproduction from spermiogenesis, posttesticular sperm maturation and capacitation to oocyte-sperm fusion. CRISP3 is epithelium-specific and found predominantly in salivary gland, pancreas and prostate, and in less abundance in the epididymis, ovary, thymus and colon. CRISP3 is up-regulated in malignant prostatic epithelium, therefore, it can be used as a potential prostate cancer biomarker.

UniProt: P54108