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Vimentin antibody (Biotin)

VIM Reactivity: Human IHC Host: Mouse Monoclonal Biotin
Catalog No. ABIN645827
  • Target See all Vimentin (VIM) Antibodies
    Vimentin (VIM)
    Reactivity
    • 304
    • 120
    • 117
    • 60
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    • 49
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    Human
    Host
    • 158
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    • 11
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    Mouse
    Clonality
    • 172
    • 144
    Monoclonal
    Conjugate
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    This Vimentin antibody is conjugated to Biotin
    Application
    • 263
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    • 97
    • 88
    • 64
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    Immunohistochemistry (IHC)
    Purpose
    Mouse Anti-Human Vimentin, Biotinylated
    Cross-Reactivity (Details)
    Vimentin antibody will recognize most mammalian Vimentin except mouse and rat.
    Characteristics
    Collagen & Extracellular Matrix Proteins
    Immunogen
    Purified Human Vimentin.
    Isotype
    IgG1
    Top Product
    Discover our top product VIM Primary Antibody
  • Application Notes
    Immunohistochemistry.< div class='ty-product-feature'>< div class='ty-product-feature__label'>Cross Reactivity< div class='ty-product-feature__value'>Vimentin antibody will recognize most mammalian Vimentin except mouse and rat.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute with H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.
    Concentration
    1 mg/ml in PBS (after reconstitution).
    Storage
    -20 °C
    Storage Comment
    -20°C
  • Target
    Vimentin (VIM)
    Alternative Name
    Vimentin (VIM Products)
    Background

    Target Description: Vimentin expression in human malignant glioma cells depends on cellular density, algorithms of drug delivery and chemo/radio treatment. Vimentin and detyrosinated microtubules provide structural support for the extensive microtentacles observed in detached tumor cells and a mechanism to promote successful metastatic spread. Primary colorectal carcinomas display aberrant expression of vimentin, and have activated Notch and TGFbeta signaling pathways. Vimentin is a strong arterial substrate for transglutaminases. Transglutaminase-mediated vimentin dimerization results in a novel unifying pathway by which vasodilatory and remodeling responses may be regulated. Ablation of vimentin expression inhibits migration and invasion of colon and breast cancer cell lines.< div class='ty-product-feature'>< div class='ty-product-feature__label'>Cross Reactivity< div class='ty-product-feature__value'>Vimentin antibody will recognize most mammalian Vimentin except mouse and rat.

    Pathways
    Caspase Cascade in Apoptosis
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