EBV LMP2A antibody
EBV LMP2A
Reactivity: Epstein-Barr Virus (EBV)
IHC (p), WB
Host: Rat
unconjugated
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- Target See all EBV LMP2A products
- EBV LMP2A (Epstein-Barr Virus Latent Membrane Protein 2A (EBV LMP2A))
- Reactivity
- Epstein-Barr Virus (EBV)
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Host
- Rat
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Conjugate
- This EBV LMP2A antibody is un-conjugated
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Application
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
- Specificity
- DS-MB-03627 recognizes latent membrane protein 2A (LMP2A) of Epstein-Barr virus (EBV). EBV is a human herpes virus, which is associated with conditions such as Hodgkin's disease and Burkitt's Lymphoma and is the causative agent in mononucleosis in adolescents. EBV latently infects B lymphocytes. Infected B cells express EBV nuclear antigens and latent proteins LMP1, LMP2A and LMP2B. LMP2A forms aggregates in the plasma membranes of B lymphocytes, where it functions as a negative regulator of the Src and Syk protein tyrosine kinases. Studies show that LMP2A blocks B-cell receptor (BCR) signal transduction in EBV immortalized B cells in vitro and may play an important role in maintaining a latent EBV infection within the peripheral blood B cells of infected individuals. DS-MB-03627 specifically recognizes LMP2A and does not cross react with LMP2B.
- Characteristics
- Rat Anti-Epstein-Barr Virus LMP2A
- Purification
- Purified
- Immunogen
- Bacterial TrpE-LMP2A fusion protein
- Isotype
- IgG2a
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- Restrictions
- For Research Use only
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- Concentration
- IgG concentration 1.0 mg/ml
- Buffer
- Phosphate buffered saline
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
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- Target
- EBV LMP2A (Epstein-Barr Virus Latent Membrane Protein 2A (EBV LMP2A))
- Alternative Name
- Epstein-Barr Virus LMP2A (EBV LMP2A Products)
- Synonyms
- - antibody, LMP2A antibody
- Target Type
- Viral Protein
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