SDF1 beta antibody

Catalog No. ABIN640076

Product Details anti-SDF1 beta Antibody

Target: SDF1 beta (SDF1b) (Stromal Cell Derived Factor 1 beta (SDF1b))

Reactivity: Human

Host: Goat

Conjugate: This SDF1 beta antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: DS-PB-01781 recognizes human SDF-1 beta, otherwise known as CXCL12b, a 72 amino acid stromal cell derived CXC chemokine, which arises from alternative splicing of the SDF-1 gene. The two isoforms, SDF-1 alpha and SDF-1 beta, share an identical amino acid sequence, except for an additional four residues in the C-terminal region of the beta isoform. SDF-1 binds with high-affinity to the G protein-coupled receptor CXCR4 (fusin) and acts as a chemoattractant for T and B lymphocytes, monocytes and migratory neurons, and is a vital factor in haematopoiesis and angiogenesis. By competitively binding to CXCR4, SDF-1 acts as an inhibitor for the CXCR4-mediated entry of HIV-1 virus into target T-cells, and the SDF-1-CXCR4 interaction is important for the regulation of trafficking of normal and malignant stem cells.

Characteristics: Goat Anti-Human SDF-1 beta

Purification: Purified

Immunogen: Recombinant human SDF-1 beta.

Isotype: IgG

Application Details

Restrictions: For Research Use only

Handling

Reconstitution: Reconstitute with 0.1ml distilled water. For long term storage the addition of 0.09% sodium azide is recommended.

Concentration: IgG concentration 1.0 mg/ml

Buffer: Phosphate buffered saline pH7.4

Storage: 4 °C

Target Details for SDF1 beta

Target: SDF1 beta (SDF1b) (Stromal Cell Derived Factor 1 beta (SDF1b))

Alternative Name: SDF1 beta (SDF1b Products)

Synonyms: Pbsf antibody, Scyb12 antibody, Sdf1 antibody, Tlsf antibody, Tpar1 antibody, sdf1a antibody, SDF-1 antibody, chemokine (C-X-C motif) ligand 12 antibody, C-X-C motif chemokine ligand 12 antibody, Cxcl12 antibody, cxcl12 antibody, CXCL12 antibody

Background: Synonyms: SDF1, SDF1A, SDF1B