PLA2G3 antibody, GIII-SPLA2 antibody, SPLA2III antibody, 9130003P18Rik antibody, phospholipase A2 group III antibody, phospholipase A2, group III antibody, PLA2G3 antibody, Pla2g3 antibody
Background
Phospholipases are a group of enzymes that hydrolyze phospholipids into fatty acids and other lipophilic molecules. PLA is subdivided into PLA1 which cleave phospholipids at the sn-1 ester bond and PLA2, which cleave at the sn-2 bond. Phospholipases are ubiquitously expressed and have diverse biological functions including roles in inflammation, cell growth, signaling and death and maintenance of membrane phospholipids.