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Prostaglandin E Synthase antibody
PTGES
Reactivity: Human
IHC (p)
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-Prostaglandin E Synthase Antibody
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Target
See all Prostaglandin E Synthase (PTGES) Antibodies
Prostaglandin E Synthase (PTGES)
Reactivity
All reactivities for Prostaglandin E Synthase antibodies
Human
Host
All hosts for Prostaglandin E Synthase antibodies
Rabbit
Clonality
All clonalities for Prostaglandin E Synthase antibodies
Polyclonal
Conjugate
All conjugates for Prostaglandin E Synthase antibodies
This Prostaglandin E Synthase antibody is un-conjugated
Application
All applications for Prostaglandin E Synthase antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Purification
Affinity chromatography purified
Immunogen
PTGES antibody was raised in rabbit using a synthetic peptide conjugated to KLH as the immunogen.
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Alternatives
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Application Details
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Application Notes
IHC-P: 10 µg/mL Optimal conditions should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
Lot specific
Buffer
Purified by Immunoaffinity Chromatography and supplied in PBS with 0.1 % NaN3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handling Advice
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
Storage
4 °C/-20 °C
Storage Comment
Store at 4 °C for short term storage. Aliquot and store at -70 °C for long term storage.
Target Details for Prostaglandin E Synthase
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Target
Prostaglandin E Synthase (PTGES)
Alternative Name
PTGES (PTGES Products )
Synonyms
ptges antibody, MGC80290 antibody, PTGES antibody, MGST-IV antibody, MGST1-L1 antibody, MGST1L1 antibody, MPGES antibody, PGES antibody, PIG12 antibody, PP102 antibody, PP1294 antibody, TP53I12 antibody, mPGES-1 antibody, 2410099E23Rik antibody, D2Ertd369e antibody, Pges antibody, mPGES antibody, MPGES-1 antibody, prostaglandin E synthase antibody, prostaglandin E synthase S homeolog antibody, PTGES antibody, ptges.S antibody, Ptges antibody
Background
Prostaglandin E synthase is an enzyme that in humans is encoded by the PTGES gene. The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53-induced apoptosis. Knockout studies in mice suggest that this gene may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses.
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