PDE8B antibody
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- Target See all PDE8B Antibodies
- PDE8B (phosphodiesterase 8B (PDE8B))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PDE8B antibody is un-conjugated
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Application
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- Affinity chromatography purified
- Immunogen
- PDE8 B antibody was raised in rabbit using a synthetic peptide conjugated to KLH as the immunogen.
- Top Product
- Discover our top product PDE8B Primary Antibody
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- Application Notes
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IHC-P: 10 µg/mL
Optimal conditions should be determined by the investigator. - Restrictions
- For Research Use only
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- Concentration
- Lot specific
- Buffer
- Purified by Immunoaffinity Chromatography and supplied in PBS with 0.1 % NaN3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Handling Advice
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 4 °C for short term storage. Aliquot and store at -70 °C for long term storage.
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- Target
- PDE8B (phosphodiesterase 8B (PDE8B))
- Alternative Name
- PDE8B (PDE8B Products)
- Synonyms
- PDE8B antibody, ADSD antibody, PPNAD3 antibody, B230331L10Rik antibody, C030047E14Rik antibody, RNPDE8B antibody, phosphodiesterase 8B antibody, high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B antibody, PDE8B antibody, LOC100468338 antibody, pde8b antibody, Pde8b antibody
- Background
- Phosphodiesterases (PDEs) are a family of related phosphohydrolyases that selectively catalyze the hydrolysis of 3' cyclic phosphate bonds in adenosine and/or guanine 3',5' cyclic monophosphate (cAMP and/or cGMP). They regulate the cellular levels, localization and duration of action of these second messengers by controlling the rate of their degradation. PDE1-11, PDE4, 7 and 8 selectively degrade cAMP. These enzymes are involved in many signal transduction pathways.
- Pathways
- Negative Regulation of Hormone Secretion, cAMP Metabolic Process
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