AGE antibody

Catalog No. ABIN636761

Product Details anti-AGE Antibody

Target: AGE (Advanced Glycation End Products (AGE))

Reactivity: Please inquire

Host: Goat

Clonality: Polyclonal

Conjugate: This AGE antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Immunogen: AGE antibody was raised in goat using glycoaldehyde-modified protein as the immunogen.

Application Details

Application Notes: ELISA: >1:4,000, WB: >1:2,000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Supplied as liquid whole serum without preservative

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Target Details for AGE

Target: AGE (Advanced Glycation End Products (AGE))

Alternative Name: AGE (AGE Products)

Synonyms: RBP antibody, RNBP antibody, renin binding protein antibody, RENBP antibody

Target Type: Chemical

Background: Glycation is a post-translational modification of proteins involving a covalent linkage between a reducing sugar, such as glucose, and a receptive amino group via the non-enzymatic Maillard reaction. During the early stages of the Maillard reaction, the aldehyde groups of the reducing sugars react with the amino groups of N-terminal amino acids to form Schiff bases, which are then converted to Amadori compounds. In the advanced stages, these Amadori compounds undergo oxidation, dehydration and condensation to form advanced glycation end-products (AGE) that are characterized by fluorescence, browning, and intra- or inter-molecular cross-linking properties. The main AGE products are pentosine and carboxymethyllysine (CML).