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AGE antibody

AGE WB, ELISA Host: Goat Polyclonal unconjugated
Catalog No. ABIN636761
  • Target See all AGE Antibodies
    AGE (Advanced Glycation End Products (AGE))
    Reactivity
    Please inquire
    Host
    • 22
    • 4
    Goat
    Clonality
    • 22
    • 4
    Polyclonal
    Conjugate
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This AGE antibody is un-conjugated
    Application
    • 23
    • 14
    • 13
    • 13
    • 9
    • 6
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA
    Immunogen
    AGE antibody was raised in goat using glycoaldehyde-modified protein as the immunogen.
    Top Product
    Discover our top product AGE Primary Antibody
  • Application Notes
    ELISA: >1:4,000, WB: >1:2,000
    Optimal conditions should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Supplied as liquid whole serum without preservative
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
  • Target
    AGE (Advanced Glycation End Products (AGE))
    Alternative Name
    AGE (AGE Products)
    Synonyms
    RBP antibody, RNBP antibody, renin binding protein antibody, RENBP antibody
    Target Type
    Chemical
    Background
    Glycation is a post-translational modification of proteins involving a covalent linkage between a reducing sugar, such as glucose, and a receptive amino group via the non-enzymatic Maillard reaction. During the early stages of the Maillard reaction, the aldehyde groups of the reducing sugars react with the amino groups of N-terminal amino acids to form Schiff bases, which are then converted to Amadori compounds. In the advanced stages, these Amadori compounds undergo oxidation, dehydration and condensation to form advanced glycation end-products (AGE) that are characterized by fluorescence, browning, and intra- or inter-molecular cross-linking properties. The main AGE products are pentosine and carboxymethyllysine (CML).
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