CLCF1 antibody

Catalog No. ABIN636624

Product Details anti-CLCF1 Antibody

Target: CLCF1 (Cardiotrophin-Like Cytokine Factor 1 (CLCF1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLCF1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Blocking Antibody (Inhibition)

Purification: Purified

Immunogen: NNT1 antibody was raised in rabbit using highly pure recombinant human NNT-1/BCSF-3 as the immunogen.

Application Details

Application Notes: Optimal conditions should be determined byt he investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized from PBS, pH 7.2.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.

Target Details for CLCF1

Target: CLCF1 (Cardiotrophin-Like Cytokine Factor 1 (CLCF1))

Alternative Name: NNT1 (CLCF1 Products)

Synonyms: clc antibody, nr6 antibody, bsf3 antibody, nnt1 antibody, ciss2 antibody, CLCF1 antibody, BSF-3 antibody, BSF3 antibody, CISS2 antibody, CLC antibody, NNT-1 antibody, NNT1 antibody, NR6 antibody, Bsf3 antibody, Clc antibody, cardiotrophin like cytokine factor 1 antibody, cardiotrophin-like cytokine factor 1 antibody, clcf1 antibody, CLCF1 antibody, Clcf1 antibody

Background: NNT-1/BCSF-3 is a neurotrophic factor with B-cell stimulating capabilities. Expressed in lymph nodes and spleen, NNT-1/BCSF-3 binds and activates glycoprotein 130 (gp130) and leukemia inhibitory factor receptor member beta (LIFR-beta) and induces tyrosine phosphorylation of these receptors. In vitro, it supports the survival of chick embryo motor and sympathetic neurons. In mice, NNT-1/BCSF-3 induces serum amyloid A, causes body weight loss and B cell hyperplasia associated with increased in serum IgG and IgM.

Molecular Weight: 22.4 kDa (predicted detection band MW)

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response