NR4A2 antibody
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- Target See all NR4A2 Antibodies
- NR4A2 (Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NR4A2 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Cross-Reactivity
- Mouse (Murine), Rat (Rattus)
- Purification
- Affinity chromatography purified
- Immunogen
- Nurr1 antibody was raised in rabbit using a synthetic peptide comprising an internal sequence of the human Nurr1 protein as the immunogen.
- Isotype
- IgG
- Top Product
- Discover our top product NR4A2 Primary Antibody
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- Application Notes
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IHC: 1:100-1:200, WB: 1:1,000-1:2,000
Optimal conditions should be determined by the investigator. - Restrictions
- For Research Use only
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- Concentration
- Lot specific
- Buffer
- Affinity purified and supplied in PBS, with 0.02 % NaN3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Handling Advice
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
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- Target
- NR4A2 (Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2))
- Alternative Name
- Nurr1 (NR4A2 Products)
- Synonyms
- nr41/42/43 antibody, Nr4a2 antibody, nurr1 antibody, not antibody, rnr1 antibody, hzf-3 antibody, tinur antibody, NGFI-B antibody, HZF-3 antibody, NOT antibody, NURR1 antibody, RNR1 antibody, TINUR antibody, Nurr1 antibody, RNR-1 antibody, TINOR antibody, ngf1b antibody, nr4a2 antibody, zgc:92696 antibody, nuclear receptor subfamily 4 group A member 2 antibody, nuclear receptor antibody, nuclear receptor subfamily 4, group A, member 2 antibody, nuclear receptor subfamily 4, group A, member 2b antibody, NR4A2 antibody, nr41/42/43 antibody, nr4a2 antibody, Nr4a2 antibody, nr4a2b antibody
- Background
- The Nurr1 gene encodes a member of the steroid-thyroid hormone- retinoid receptor superfamily. The encoded protein may act as a transcription factor. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson's. Nurr1 is a stem cell marker and cooperates with PITX3 to promote terminal maturation of Mouse and human embryonic stem cell cultures to a midbrain dopamine neuron phenotype.
- Pathways
- Nuclear Receptor Transcription Pathway, Dopaminergic Neurogenesis, Steroid Hormone Mediated Signaling Pathway
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