NEIL3 antibody (AA 164-177)

Catalog No. ABIN636292

Product Details anti-NEIL3 Antibody

Target: NEIL3 (Nei Endonuclease VIII-Like 3 (NEIL3))

Binding Specificity: AA 164-177

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NEIL3 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity chromatography purified

Immunogen: NEI3 antibody was raised in rabbit using AA 164-177 (LRAESEVKKQKGRMLG) of the human NEI3 protein as the immunogen.

Isotype: IgG

Application Details

Application Notes: WB: 1:500
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: Affinity purified IgG supplied in PBS with 0.02 % NaN3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Target Details for NEIL3

Target: NEIL3 (Nei Endonuclease VIII-Like 3 (NEIL3))

Alternative Name: NEI3 (NEIL3 Products)

Background: Endonuclease VIII-like 1 (NEI1) is an enzyme that in humans is encoded by the NEIL1 gene. NEI1 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction.

Pathways: DNA Damage Repair