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NDUFA13 antibody (AA 159-172)
NDUFA13
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-NDUFA13 Antibody
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Target
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NDUFA13
(NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 13 (NDUFA13))
Binding Specificity
All epitopes for NDUFA13 antibodies
AA 159-172
Reactivity
All reactivities for NDUFA13 antibodies
Human
Host
All hosts for NDUFA13 antibodies
Rabbit
Clonality
All clonalities for NDUFA13 antibodies
Polyclonal
Conjugate
All conjugates for NDUFA13 antibodies
This NDUFA13 antibody is un-conjugated
Application
All applications for NDUFA13 antibodies
Western Blotting (WB)
Cross-Reactivity (Details)
This antibodys immunogens shares 85 % sequence identity with its Mouse and rat homologs.
Purification
Affinity chromatography purified
Immunogen
GRIM19 antibody was raised in rabbit using AA 159-172 QAETDRRTLQMLRE of the human GRIM-19 protein as the immunogen.
Isotype
IgG
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Application Details
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Application Notes
WB: 1:500-1:1,000 Optimal conditions should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
Lot specific
Buffer
Affinity purified IgG supplied in PBS with 0.02 % NaN3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handling Advice
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
Storage
4 °C/-20 °C
Storage Comment
Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
Target Details for NDUFA13
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Target
NDUFA13
(NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 13 (NDUFA13))
Alternative Name
GRIM19 (NDUFA13 Products )
Synonyms
GRIM-19 antibody, Ndufa13 antibody, B16.6 antibody, CDA016 antibody, GRIM19 antibody, 2700054G14Rik antibody, AU022060 antibody, CGI-39 antibody, Grim19 antibody, RGD1565358 antibody, YJEFN3 antibody, NADH:ubiquinone oxidoreductase subunit A13 antibody, NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13 antibody, cell death-regulatory protein GRIM19 antibody, GRIM-19 protein antibody, NADH:ubiquinone oxidoreductase subunit A13 L homeolog antibody, ndufa13 antibody, LOC655421 antibody, Ndufa13 antibody, CpipJ_CPIJ000908 antibody, Bm1_18845 antibody, ndufa13.L antibody, NDUFA13 antibody
Background
Antisense expression of Genes associated with Retinoid-IFN-induced Mortality (GRIM), GRIM-19 confers a strong resistance against IFN/RA-induced death by reducing the intracellular levels of GRIM-19 protein. Overexpression of GRIM-19 enhances cell death in response to IFN/RA. GRIM-19 is primarily a nuclear protein whose expression is induced by the IFN/RA combination.
Pathways
Protein targeting to Nucleus , Negative Regulation of intrinsic apoptotic Signaling
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