Kallikrein 15 antibody (AA 75-87)

Catalog No. ABIN636239

Product Details anti-Kallikrein 15 Antibody

Target: Kallikrein 15 (KLK15) (Kallikrein-Related Peptidase 15 (KLK15))

Binding Specificity: AA 75-87

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Kallikrein 15 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity (Details): This antibodys immunogens shares 92 % sequence identity with its Mouse, and rat homologs.

Purification: Affinity chromatography purified

Immunogen: KLK15 antibody was raised in rabbit using AA 75-87 [HNLRKRDGPEQLR] of the 28 kDa human KLK15 protein as the immunogen.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:1,000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: Affinity purified IgG supplied in PBS with 0.02 % NaN3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Target Details for Kallikrein 15

Target: Kallikrein 15 (KLK15) (Kallikrein-Related Peptidase 15 (KLK15))

Alternative Name: KLK15 (KLK15 Products)

Synonyms: ACO antibody, HSRNASPH antibody, kallikrein related-peptidase 15 antibody, kallikrein related peptidase 15 antibody, kallikrein-related peptidase 15 antibody, Klk15 antibody, KLK15 antibody

Background: This is a novel human kallikrein gene. Kallikreins are a subgroup of serine proteases and are implicated in carcinogenesis. KLK15 is up-regulated in more aggressive forms of prostate cancer, which indicates its potential use as a diagnostic or prognostic marker for prostate cancer. The gene contains multiple polyadenylation sites and is alternatively spliced. Four splice variants, each encoding a distinct isoform, have been described.

Pathways: Complement System