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IgA antibody (Middle Region)

Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN635180
  • Target See all IgA Antibodies
    IgA
    Binding Specificity
    Middle Region
    Reactivity
    Human
    Host
    • 1
    Rabbit
    Clonality
    • 1
    Polyclonal
    Conjugate
    • 1
    This IgA antibody is un-conjugated
    Application
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Specificity
    PIGA antibody was raised against the middle region of PIGA
    Purification
    Affinity purified
    Immunogen
    PIGA antibody was raised using the middle region of PIGA corresponding to a region with amino acids SVKSLCEGLEKAIFQLKSGTLPAPENIHNIVKTFYTWRNVAERTEKVYDR
  • Application Notes
    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.
    Comment

    PIGA Blocking Peptide, catalog no. 33R-8916, is also available for use as a blocking control in assays to test for specificity of this PIGA antibody

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of PIGA antibody in PBS
    Concentration
    Lot specific
    Buffer
    PBS
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • Target
    IgA
    Abstract
    IgA Products
    Synonyms
    MB-1 antibody, IG-alpha antibody, IGA antibody, IgA antibody, Igh-2 antibody, CD79a molecule antibody, immunoglobulin heavy constant alpha antibody, CD79A antibody, Igha antibody
    Target Type
    Antibody
    Background
    PIGA is a protein required for synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in the biosynthetic pathway of GPI anchor. The GPI anchor is a glycolipid found on many blood cells and which serves to anchor proteins to the cell surface. Paroxysmal nocturnal hemoglobinuria, an acquired hematologic disorder, has been shown to result from mutations in this gene.
    Molecular Weight
    19 kDa (MW of target protein)
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