COLEC12 antibody (N-Term)

Catalog No. ABIN634519

Product Details anti-COLEC12 Antibody

Target: COLEC12 (Collectin Sub-Family Member 12 (COLEC12))

Binding Specificity: N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COLEC12 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: COLEC12 antibody was raised against the N terminal of COLEC12

Purification: Affinity purified

Immunogen: COLEC12 antibody was raised using the N terminal of COLEC12 corresponding to a region with amino acids AISTNSELSTFRSDILDLRQQLREITEKTSKNKDTLEKLQASGDALVDRQ

Application Details

Application Notes: WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

COLEC12 Blocking Peptide, catalog no. 33R-1281, is also available for use as a blocking control in assays to test for specificity of this COLEC12 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of COLEC12 antibody in PBS

Concentration: Lot specific

Buffer: PBS

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Target Details for COLEC12

Target: COLEC12 (Collectin Sub-Family Member 12 (COLEC12))

Alternative Name: COLEC12 (COLEC12 Products)

Synonyms: COLEC12 antibody, CLP1 antibody, NSR2 antibody, SCARA4 antibody, SRCL antibody, CL-P1 antibody, Scara4 antibody, hm:zeh0853 antibody, id:ibd2826 antibody, sb:cb377 antibody, si:ch211-212m21.5 antibody, collectin subfamily member 12 antibody, collectin sub-family member 12 antibody, COLEC12 antibody, colec12 antibody, Colec12 antibody

Background: COLEC12 is a member of the C-lectin family,proteins that possess collagen-like sequences and carbohydrate recognition domains. This protein is a scavenger receptor, a cell surface glycoprotein that can bind to carbohydrate antigens on microorganisms facilitating their recognition and removal. In addition, these receptors can recognise oxidized phospholipids so they may also participate in removing oxidatively damaged or apoptotic cells.

Molecular Weight: 81 kDa (MW of target protein)

Pathways: Activation of Innate immune Response