Ectodysplasin A antibody (Middle Region)

Catalog No. ABIN634516

Product Details anti-Ectodysplasin A Antibody

Target: Ectodysplasin A (EDA)

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ectodysplasin A antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: Ectodysplasin A antibody was raised against the middle region of EDA

Purification: Affinity purified

Immunogen: Ectodysplasin A antibody was raised using the middle region of EDA corresponding to a region with amino acids GPPGPPGPQGPPGLQGPSGAADKAGTRENQPAVVHLQGQGSAIQVKNDLS

Application Details

Application Notes: WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

Ectodysplasin A Blocking Peptide, catalog no. 33R-3477, is also available for use as a blocking control in assays to test for specificity of this Ectodysplasin A antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of EDA antibody in PBS

Concentration: Lot specific

Buffer: PBS

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Target Details for Ectodysplasin A

Target: Ectodysplasin A (EDA)

Alternative Name: Ectodysplasin A (EDA Products)

Synonyms: ECTD1 antibody, ED1 antibody, ED1-A1 antibody, ED1-A2 antibody, EDA-A1 antibody, EDA-A2 antibody, EDA1 antibody, EDA2 antibody, HED antibody, HED1 antibody, ODT1 antibody, STHAGX1 antibody, XHED antibody, XLHED antibody, si:ch73-223d24.5 antibody, Ed1 antibody, Eda-A1 antibody, Eda-A2 antibody, Ta antibody, tabby antibody, RGD1563178 antibody, ectodysplasin A antibody, ectodysplasin-A antibody, EDA antibody, eda antibody, Eda antibody

Background: EDA is a type II membrane protein that can be cleaved by furin to produce a secreted form. It belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene.

Molecular Weight: 41 kDa (MW of target protein)

Pathways: Tube Formation