C4B antibody
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- Target See all C4B (C4b) Antibodies
- C4B (C4b) (Complement Component C4b (C4b))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This C4B antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- Affinity purified
- Immunogen
- Complement C4 b antibody was raised using a synthetic peptide corresponding to a region with amino acids QTDQPIYNPGQRVRYRVFALDQKMRPSTDTITVMVENSHGLRVRKKEVYM
- Top Product
- Discover our top product C4b Primary Antibody
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- Application Notes
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. - Comment
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Complement C4b Blocking Peptide, catalog no. 33R-7746, is also available for use as a blocking control in assays to test for specificity of this Complement C4b antibody
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of C0 antibody in PBS
- Concentration
- Lot specific
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- Target
- C4B (C4b) (Complement Component C4b (C4b))
- Alternative Name
- Complement C4b (C4b Products)
- Synonyms
- C4B1 antibody, C4B12 antibody, C4B2 antibody, C4B3 antibody, C4B5 antibody, C4BD antibody, C4B_2 antibody, C4F antibody, CH antibody, CO4 antibody, CPAMD3 antibody, C4 antibody, C4A2 antibody, C4A3 antibody, C4A4 antibody, C4A6 antibody, C4AD antibody, C4S antibody, CPAMD2 antibody, RG antibody, wu:fi14a03 antibody, C4B antibody, DKFZP469I0332 antibody, Slp antibody, Ss antibody, C4-2 antibody, C4l antibody, complement C4B (Chido blood group) antibody, complement C4A (Rodgers blood group) antibody, complement component 4 antibody, complement C4-B antibody, complement component 4B (Chido blood group) antibody, complement component 4A (Rodgers blood group) antibody, C4B antibody, C4A antibody, c4 antibody, LOC462577 antibody, C4a antibody, C4b antibody
- Background
- C4B is the basic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus. This gene encodes the basic form of complement factor 4, part of the classical activation pathway.
- Molecular Weight
- 33 kDa (MW of target protein)
- Pathways
- Complement System
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