CENPH antibody (N-Term)

Catalog No. ABIN634089

Product Details anti-CENPH Antibody

Target: CENPH (Centromere Protein H (CENPH))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CENPH antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: CENPH antibody was raised against the N terminal of CENPH

Purification: Affinity purified

Immunogen: CENPH antibody was raised using the N terminal of CENPH corresponding to a region with amino acids MEEQPQMQDADEPADSGGEGRAGGPPQVAGAQAACSEDRMTLLLRLRAQT

Application Details

Application Notes: WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

CENPH Blocking Peptide, catalog no. 33R-5910, is also available for use as a blocking control in assays to test for specificity of this CENPH antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of CENPH antibody in PBS

Concentration: Lot specific

Buffer: PBS

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Target Details for CENPH

Target: CENPH (Centromere Protein H (CENPH))

Alternative Name: CENPH (CENPH Products)

Synonyms: 1700021I11Rik antibody, 2410018A12Rik antibody, 2610042E16Rik antibody, 2810046K12Rik antibody, AU044255 antibody, CENP-H antibody, ENP antibody, si:dkey-186m8.3 antibody, cenp-h antibody, centromere protein H antibody, centromere protein H pseudogene antibody, CENPH antibody, Cenph antibody, cenph antibody, LOC100356112 antibody, LOC101788801 antibody

Background: Centromere and kinetochore proteins play a critical role in centromere structure, kinetochore formation, and sister chromatid separation. CENPH colocalizes with inner kinetochore plate proteins CENP-A and CENP-C in both interphase and metaphase. It localizes outside of centromeric heterochromatin, where CENP-B is localized, and inside the kinetochore corona, where CENP-E is localized during prometaphase. It is thought that this protein can bind to itself, as well as to CENP-A, CENP-B or CENP-C. Multimers of the protein localize constitutively to the inner kinetochore plate and play an important role in the organization and function of the active centromere-kinetochore complex.

Molecular Weight: 27 kDa (MW of target protein)