PPOX antibody (N-Term)

Catalog No. ABIN633874

Product Details anti-PPOX Antibody

Target: PPOX (Protoporphyrinogen Oxidase (PPOX))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPOX antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: PPOX antibody was raised against the N terminal of PPOX

Purification: Affinity purified

Immunogen: PPOX antibody was raised using the N terminal of PPOX corresponding to a region with amino acids SSERLGGWIRSVRGPNGAIFELGPRGIRPAGALGARTLLLVSELGLDSEV

Application Details

Application Notes: WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

PPOX Blocking Peptide, catalog no. 33R-8796, is also available for use as a blocking control in assays to test for specificity of this PPOX antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of PPOX antibody in PBS

Concentration: Lot specific

Buffer: PBS

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Target Details for PPOX

Target: PPOX (Protoporphyrinogen Oxidase (PPOX))

Alternative Name: PPOX (PPOX Products)

Background: This gene encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. Mutations in this gene cause variegate porphyria, an autosomal dominant disorder of heme metabolism resulting from a deficiency in protoporphyrinogen oxidase, an enzyme located on the inner mitochondrial membrane. Alternatively spliced transcript variants encoding the same protein have been identified.

Molecular Weight: 51 kDa (MW of target protein)

Pathways: Synaptic Membrane, Feeding Behaviour