Manic Fringe antibody (C-Term)
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- Target See all Manic Fringe (MFNG) Antibodies
- Manic Fringe (MFNG) (MFNG)
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Binding Specificity
- C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Manic Fringe antibody is un-conjugated
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Application
- Western Blotting (WB)
- Specificity
- MFNG antibody was raised against the C terminal of MFNG
- Purification
- Affinity purified
- Immunogen
- MFNG antibody was raised using the C terminal of MFNG corresponding to a region with amino acids QLLRTAQLPEQVTLSYGVFEGKLNVIKLQGPFSPEEDPSRFRSLHCLLYP
- Top Product
- Discover our top product MFNG Primary Antibody
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- Application Notes
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WB: 0.25 µg/mL
Optimal conditions should be determined by the investigator. - Comment
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MFNG Blocking Peptide, catalog no. 33R-7632, is also available for use as a blocking control in assays to test for specificity of this MFNG antibody
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of MFNG antibody in PBS
- Concentration
- Lot specific
- Buffer
- PBS
- Handling Advice
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- Target
- Manic Fringe (MFNG) (MFNG)
- Alternative Name
- MFNG (MFNG Products)
- Synonyms
- AW546563 antibody, MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase antibody, MFNG antibody, Mfng antibody
- Background
- MFNG is one of the evolutionarily conserved secreted proteins that act in the Notch receptor pathway to demarcate boundaries during embryonic development. This gene is a member of the fringe gene family which also includes Radical and Lunatic fringe. They all encode evolutionarily conserved secreted proteins that act in the Notch receptor pathway to demarcate boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta1,3 N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling.
- Molecular Weight
- 36 kDa (MW of target protein)
- Pathways
- Notch Signaling
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