PAPOLG antibody

Catalog No. ABIN633283

Product Details anti-PAPOLG Antibody

Target: PAPOLG (Poly(A) Polymerase gamma (PAPOLG))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAPOLG antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purified

Immunogen: PAPOLG antibody was raised using a synthetic peptide corresponding to a region with amino acids SVDAIGGESMPIPTIDTSRKKRLPSKELPDSSSPVPANNIRVIKNSIRLT

Application Details

Application Notes: WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

PAPOLG Blocking Peptide, catalog no. 33R-8903, is also available for use as a blocking control in assays to test for specificity of this PAPOLG antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of PAPOLG antibody in PBS

Concentration: Lot specific

Buffer: PBS

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Target Details for PAPOLG

Target: PAPOLG (Poly(A) Polymerase gamma (PAPOLG))

Alternative Name: PAPOLG (PAPOLG Products)

Synonyms: zgc:63762 antibody, 9630006B20Rik antibody, poly(A) polymerase gamma antibody, poly(A) polymerase gamma L homeolog antibody, papolg antibody, papolg.L antibody, PAPOLG antibody, Papolg antibody

Background: PAPOLG is a member of the poly(A) polymerase family which catalyzes template-independent extension of the 3' end of a DNA/RNA strand. This enzyme shares 60% identity to the well characterized poly(A) polymerase II (PAPII) at the amino acid level. These two enzymes have similar organization of structural and functional domains. This enzyme is exclusively localized in the nucleus and exhibits both nonspecific and CPSF (cleavage and polyadenylation specificity factor)/AAUAAA-dependent polyadenylation activity.

Molecular Weight: 83 kDa (MW of target protein)