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NXF1 antibody (N-Term)

NXF1 Reactivity: Human, Dog WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN633230
  • Target See all NXF1 Antibodies
    NXF1 (Nuclear RNA Export Factor 1 (NXF1))
    Binding Specificity
    • 13
    • 12
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 57
    • 8
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    Human, Dog
    Host
    • 57
    • 1
    Rabbit
    Clonality
    • 49
    • 9
    Polyclonal
    Conjugate
    • 31
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This NXF1 antibody is un-conjugated
    Application
    • 40
    • 22
    • 20
    • 10
    • 9
    • 7
    • 4
    • 1
    Western Blotting (WB)
    Specificity
    NXF1 antibody was raised against the N terminal of NXF1
    Purification
    Affinity purified
    Immunogen
    NXF1 antibody was raised using the N terminal of NXF1 corresponding to a region with amino acids RPNRRGDTWHDRDRIHVTVRRDRAPPERGGAGTSQDGTSKNWFKITIPYG
    Top Product
    Discover our top product NXF1 Primary Antibody
  • Application Notes
    WB: 0.5 µg/mL
    Optimal conditions should be determined by the investigator.
    Comment

    NXF1 Blocking Peptide, catalog no. 33R-8098, is also available for use as a blocking control in assays to test for specificity of this NXF1 antibody

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of NXF1 antibody in PBS
    Concentration
    Lot specific
    Buffer
    PBS
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • Target
    NXF1 (Nuclear RNA Export Factor 1 (NXF1))
    Alternative Name
    NXF1 (NXF1 Products)
    Synonyms
    im:7156527 antibody, wu:fc12d06 antibody, MGC82224 antibody, NXF1 antibody, tap antibody, mex67 antibody, MEX67 antibody, TAP antibody, Mex67 antibody, Mvb1 antibody, Tap antibody, Mex67h antibody, nuclear RNA export factor 1 antibody, nuclear RNA export factor 1 S homeolog antibody, Nuclear RNA export factor 1 antibody, nxf1 antibody, nxf1.S antibody, NXF1 antibody, LOC100113601 antibody, Tsp_03999 antibody, Nxf1 antibody, nxf-1 antibody
    Background
    NXF1 is one member of a family of nuclear RNA export factor. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. NXF1 shuttles between the nucleus and the cytoplasm and binds in vivo to poly(A)+ RNA. NXF1 overcomes the mRNA export block caused by the presence of saturating amounts of CTE (constitutive transport element) RNA of type D retroviruses.
    Molecular Weight
    68 kDa (MW of target protein)
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