FGFR1OP antibody (N-Term)

Catalog No. ABIN632972

Product Details anti-FGFR1OP Antibody

Target: FGFR1OP (FGFR1 Oncogene Partner (FGFR1OP))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FGFR1OP antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: FGFR1 OP antibody was raised against the N terminal of FGFR1 P

Purification: Affinity purified

Immunogen: FGFR1 OP antibody was raised using the N terminal of FGFR1 P corresponding to a region with amino acids FLQFFNLDFTLAVFQPETSTLQGLEGRENLARDLGIIEAEGTVGGPLLLE

Application Details

Application Notes: WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

FGFR1OP Blocking Peptide, catalog no. 33R-2977, is also available for use as a blocking control in assays to test for specificity of this FGFR1OP antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of FGFR0 P antibody in PBS

Concentration: Lot specific

Buffer: PBS

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Target Details for FGFR1OP

Target: FGFR1OP (FGFR1 Oncogene Partner (FGFR1OP))

Alternative Name: FGFR1OP (FGFR1OP Products)

Synonyms: 4930553O10Rik antibody, FOP antibody, ccr6a antibody, zgc:86782 antibody, fgfr1op antibody, Fgfr1op antibody, MGC132198 antibody, C1orf77 antibody, C3H1orf77 antibody, SRAG antibody, Fgfr1 oncogene partner antibody, FGFR1 oncogene partner antibody, FGFR1 oncogene partner L homeolog antibody, chromatin target of PRMT1 antibody, Fgfr1op antibody, FGFR1OP antibody, fgfr1op antibody, fgfr1op.L antibody, CHTOP antibody

Background: FGFR1OP is a largely hydrophilic protein postulated to be a leucine-rich protein family member. A t (6,8)(q27,p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. This gene is thought to play an important role in normal proliferation and differentiation of the erythroid lineage.

Molecular Weight: 42 kDa (MW of target protein)

Pathways: M Phase, Maintenance of Protein Location, SARS-CoV-2 Protein Interactome