FBXL2 antibody (N-Term)

Catalog No. ABIN631664

Product Details anti-FBXL2 Antibody

Target: FBXL2 (F-Box and Leucine-Rich Repeat Protein 2 (FBXL2))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXL2 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: FBXL2 antibody was raised against the N terminal of FBXL2

Purification: Affinity purified

Immunogen: FBXL2 antibody was raised using the N terminal of FBXL2 corresponding to a region with amino acids NISKRCGGFLRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDS

Application Details

Application Notes: WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

FBXL2 Blocking Peptide, catalog no. 33R-6734, is also available for use as a blocking control in assays to test for specificity of this FBXL2 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of FBXL2 antibody in PBS

Concentration: Lot specific

Buffer: PBS

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Target Details for FBXL2

Target: FBXL2 (F-Box and Leucine-Rich Repeat Protein 2 (FBXL2))

Alternative Name: FBXL2 (FBXL2 Products)

Synonyms: FBL2 antibody, FBL3 antibody, 2810423A21Rik antibody, Fbl3 antibody, RGD1562243 antibody, fbxl20 antibody, sb:cb783 antibody, zgc:73374 antibody, Fbl2 antibody, Fbxl2 antibody, F-box and leucine rich repeat protein 2 antibody, F-box and leucine-rich repeat protein 2 antibody, F-box and leucine-rich repeat protein 20 antibody, FBXL2 antibody, Fbxl2 antibody, fbxl2 antibody, Fbxl20 antibody

Background: FBXL2 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. FBXL2 belongs to the Fbls class and, in addition to an F-box, contains 12 tandem leucine-rich repeats.

Molecular Weight: 47 kDa (MW of target protein)