SPTLC2 antibody (N-Term)

Catalog No. ABIN631161

Product Details anti-SPTLC2 Antibody

Target: SPTLC2 (serine Palmitoyltransferase, Long Chain Base Subunit 2 (SPTLC2))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPTLC2 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: SPTLC2 antibody was raised against the N terminal of SPTLC2

Purification: Affinity purified

Immunogen: SPTLC2 antibody was raised using the N terminal of SPTLC2 corresponding to a region with amino acids VLTYVGYGVLTLFGYLRDFLRYWRIEKCHHATEREEQKDFVSLYQDFENF

Application Details

Application Notes: WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

SPTLC2 Blocking Peptide, catalog no. 33R-9690, is also available for use as a blocking control in assays to test for specificity of this SPTLC2 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of SPTLC2 antibody in PBS

Concentration: Lot specific

Buffer: PBS

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Target Details for SPTLC2

Target: SPTLC2 (serine Palmitoyltransferase, Long Chain Base Subunit 2 (SPTLC2))

Alternative Name: SPTLC2 (SPTLC2 Products)

Synonyms: HSN1C antibody, LCB2 antibody, LCB2A antibody, NSAN1C antibody, SPT2 antibody, hLCB2a antibody, sptlc2 antibody, zgc:110661 antibody, AI173915 antibody, mKIAA0526 antibody, Pomt2 antibody, LCB2a antibody, SPTLC2 antibody, serine palmitoyltransferase long chain base subunit 2 antibody, serine palmitoyltransferase 2 antibody, serine palmitoyltransferase, long chain base subunit 2 S homeolog antibody, serine palmitoyltransferase, long chain base subunit 2a antibody, serine palmitoyltransferase, long chain base subunit 2 antibody, SPTLC2 antibody, LOC100446763 antibody, sptlc2 antibody, sptlc2.S antibody, sptlc2a antibody, Sptlc2 antibody

Background: SPTLC2 is a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I.

Molecular Weight: 63 kDa (MW of target protein)