H2AFY antibody (N-Term)
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- Target See all H2AFY Antibodies
- H2AFY (H2A Histone Family, Member Y (H2AFY))
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Binding Specificity
- N-Term
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Reactivity
- Human, Rat, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This H2AFY antibody is un-conjugated
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Application
- Western Blotting (WB)
- Specificity
- H2 AFY antibody was raised against the N terminal of H2 FY
- Purification
- Affinity purified
- Immunogen
- H2 AFY antibody was raised using the N terminal of H2 FY corresponding to a region with amino acids HPKYRIGVGAPVYMAAVLEYLTAEILELAGNAARDNKKGRVTPRHILLAV
- Top Product
- Discover our top product H2AFY Primary Antibody
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- Application Notes
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. - Comment
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H2AFY Blocking Peptide, catalog no. 33R-3812, is also available for use as a blocking control in assays to test for specificity of this H2AFY antibody
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of H0 FY antibody in PBS
- Concentration
- Lot specific
- Buffer
- PBS
- Handling Advice
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- Target
- H2AFY (H2A Histone Family, Member Y (H2AFY))
- Alternative Name
- H2AFY (H2AFY Products)
- Synonyms
- H2A.y antibody, H2A/y antibody, H2AF12M antibody, H2AFJ antibody, MACROH2A1.1 antibody, mH2A1 antibody, macroH2A1.2 antibody, mH2a1 antibody, macroH2A1 antibody, wu:fa93c12 antibody, zgc:136891 antibody, h2a.y antibody, h2a/y antibody, h2af12m antibody, h2afj antibody, macroh2a antibody, mh2a1 antibody, core histone macro-H2A.1 antibody, H2A histone family, member Y antibody, H2A histone family member Y antibody, H2A histone family member Y L homeolog antibody, LOC100230612 antibody, H2AFY antibody, LOC481514 antibody, H2afy antibody, h2afy antibody, h2afy.L antibody
- Background
- Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. H2AFY is a member of the histone H2A family. It replaces conventional H2A histones in a subset of nucleosomes where it represses transcription and participates in stable X chromosome inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms.
- Molecular Weight
- 39 kDa (MW of target protein)
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