RNF128 antibody (C-Term)

Catalog No. ABIN630446

Product Details anti-RNF128 Antibody

Target: RNF128 (Ring Finger Protein 128 (RNF128))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNF128 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: RNF128 antibody was raised against the C terminal of RNF128

Purification: Purified

Immunogen: RNF128 antibody was raised using the C terminal of RNF128 corresponding to a region with amino acids LEEHVQSTNESLQLVNHEANSVAVDVIPHVDNPTFEEDETPNQETAVREI

Application Details

Application Notes: WB: 1.25 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

RNF128 Blocking Peptide, catalog no. 33R-4889, is also available for use as a blocking control in assays to test for specificity of this RNF128 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of RNF128 antibody in PBS

Concentration: Lot specific

Buffer: PBS

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Target Details for RNF128

Target: RNF128 (Ring Finger Protein 128 (RNF128))

Alternative Name: RNF128 (RNF128 Products)

Background: RNF128 is a type I transmembrane protein that localizes to the endocytic pathway. This protein contains a RING zinc-finger motif and has been shown to possess E3 ubiquitin ligase activity. Expression of RNF128 in retrovirally transduced T cell hybridoma significantly inhibits activation-induced IL2 and IL4 cytokine production. Induced expression of RNF128 was observed in anergic CD4(+) T cells, which suggested a role in the induction of anergic phenotype.

Molecular Weight: 47 kDa (MW of target protein)