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IL-10RA antibody (N-Term)

IL10RA Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN630438
  • Target See all IL-10RA (IL10RA) Antibodies
    IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))
    Binding Specificity
    • 11
    • 10
    • 9
    • 7
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 83
    • 38
    • 19
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 75
    • 13
    • 10
    • 2
    Rabbit
    Clonality
    • 76
    • 22
    • 1
    Polyclonal
    Conjugate
    • 53
    • 9
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IL-10RA antibody is un-conjugated
    Application
    • 65
    • 32
    • 18
    • 14
    • 13
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Specificity
    IL10 R Alpha antibody was raised against the N terminal of IL10 A
    Purification
    Purified
    Immunogen
    IL10 R Alpha antibody was raised using the N terminal of IL10 A corresponding to a region with amino acids GSVNLEIHNGFILGKIQLPRPKMAPANDTYESIFSHFREYEIAIRKVPGN
    Top Product
    Discover our top product IL10RA Primary Antibody
  • Application Notes
    WB: 5 µg/mL
    Optimal conditions should be determined by the investigator.
    Comment

    IL10R Alpha Blocking Peptide, catalog no. 33R-3595, is also available for use as a blocking control in assays to test for specificity of this IL10R Alpha antibody

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of IL10 A antibody in PBS
    Concentration
    Lot specific
    Buffer
    PBS
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • Target
    IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))
    Alternative Name
    IL10R alpha (IL10RA Products)
    Synonyms
    IL10R1 antibody, IL10RA antibody, CD210 antibody, CD210a antibody, CDW210A antibody, HIL-10R antibody, IL-10R1 antibody, IL10R antibody, AW553859 antibody, CDw210 antibody, CDw210a antibody, Il10r antibody, mIL-10R antibody, interleukin 10 receptor subunit alpha antibody, interleukin 10 receptor, alpha antibody, IL10RA antibody, Il10ra antibody
    Background
    IL10RA is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases.
    Molecular Weight
    61 kDa (MW of target protein)
    Pathways
    Growth Factor Binding
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