RNMT antibody
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- Target See all RNMT Antibodies
- RNMT (RNA Guanine-7 Methyltransferase (RNMT))
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Reactivity
- Human, Rat, Cow, Dog, Hamster
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This RNMT antibody is un-conjugated
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Application
- Immunohistochemistry (IHC)
- Purpose
- Mouse anti-Human/Cow/Dog/Hamster/Rat TAG-72 Antibody [IHC only]
- Specificity
- Cytoplasmic and cell surface
- Purification
- The membrane-enriched fraction of a human breast carcinoma liver metastasis was used as the immunogen for this TAG-72 antibody.
- Immunogen
- The membrane-enriched fraction of a human breast carcinoma liver metastasis was used as the immunogen for this TAG-72 antibody.
- Top Product
- Discover our top product RNMT Primary Antibody
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- Application Notes
- Prediluted format : incubate for 30 min at RT (2)
- Restrictions
- For Research Use only
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- Buffer
- Prediluted in 1X PBS ( pH 7.4) with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, For IHC use only
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- Target
- RNMT (RNA Guanine-7 Methyltransferase (RNMT))
- Alternative Name
- mRNA cap guanine-N7 methyltransferase (RNMT Products)
- Synonyms
- xCMT1 antibody, MET antibody, RG7MT1 antibody, hCMT1c antibody, 2610002P10Rik antibody, AI848273 antibody, Rg7mt1 antibody, mKIAA0398 antibody, rnmt antibody, im:6910566 antibody, wu:fi09c12 antibody, RNA (guanine-7-) methyltransferase L homeolog antibody, RNA guanine-7 methyltransferase antibody, RNA (guanine-7-) methyltransferase antibody, rnmt.L antibody, RNMT antibody, Rnmt antibody, rnmt antibody
- Background
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Target Description: This antibody recognizes an oncofetal antigen of 220 kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. This antibody defines the mucin-carried sialylated-Tn epitope. TAG-72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80 % sensitivity and 93 % specificity for pulmonary adenocarcinoma. Therefore, TAG-72 is a useful marker to distinguish between mesothelioma and adenocarcinoma. However, false positive reactions can occur so results must be interpreted with the utmost caution. This antibody may be useful in the differentiation of non-small cell carcinomas from small cell carcinomas of the lung. The combined use of TAG-72 Ab with a GCDFP-15 Ab is valuable in the diagnosis of apocrine carcinoma.
Gene Symbol: tag-72 C25A1.3
- Gene ID
- 182875
- UniProt
- Q9XVS1
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